The review article COCONUT discusses the options to extend anticoagulant therapy after completing the main anticoagulant therapy course in patients, who survived pulmonary embolism.It presents the results of randomized RE-MEDY and RE-SONATE studies of dabigatran, EINSTEIN-Extension study of rivaroxaban and AMPLIFY-Extension study of apixaban, which
Microglia, the resident immune cells of the brain, can take on a range of pro- or anti-inflammatory phenotypes to maintain homeostasis.However, the sustained activation of pro-inflammatory microglia can lead to a state of chronic neuroinflammation characterized by high concentrations of neurotoxic soluble factors throughout the brain.In healthy bra
Loneliness and social isolation affect more than 1 in 4 community-dwelling older adults in the United States, who may also require long-term care support.Despite being seen as a solution to the long-term care crisis, most older adults prefer to age in place rather than using skilled nursing Heater Assy facilities.However, in-home care is unsustaina